PK / PD
Pharmacokinetic & Pharmacodynamic Modeling
Quantitative analysis of drug exposure and response.
Overview
PK/PD modeling integrates exposure and response data to investigate dose, time course and variability and to support development hypotheses.
Each modeling strategy must be tailored to the available data, scientific question and applicable regulatory expectations.
Potential applications
- Exposure–response assessment
- Dose regimen exploration
- Variability and covariate investigation
Illustrative outputs
- Analysis plan
- Model diagnostics and simulations
- Interpretation and technical report
Discuss a specific development question
We can start by defining the scientific objective and available evidence.